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Double-strand DNA breaks recruit the centromeric histone CENP-A
The histone H3 variant CENP-A is required for epigenetic specification of centromere identity through a loading mechanism independent of DNA sequence. Using multiphoton absorption and DNA cleavage at unique sites by I-SceI endonuclease, we demonstrate that CENP-A is rapidly recruited to double-stran...
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| Autores principales: | , , , , , , |
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| Formato: | Artigo |
| Lenguaje: | Inglês |
| Publicado: |
National Academy of Sciences
2009
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| Materias: | |
| Acceso en línea: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2747192/ https://ncbi.nlm.nih.gov/pubmed/19717431 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0908233106 |
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