Cdon deficiency causes cardiac remodeling through hyperactivation of WNT/β-catenin signaling

On pathological stress, Wnt signaling is reactivated and induces genes associated with cardiac remodeling and fibrosis. We have previously shown that a cell surface receptor Cdon (cell-adhesion associated, oncogene regulated) suppresses Wnt signaling to promote neuronal differentiation however its r...

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Dettagli Bibliografici
Pubblicato in:Proc Natl Acad Sci U S A
Autori principali: Jeong, Myong-Ho, Kim, Hyun-Ji, Pyun, Jung-Hoon, Choi, Kyu-Sil, Lee, Dong I., Solhjoo, Soroosh, O'Rourke, Brian, Tomaselli, Gordon F., Jeong, Dong Seop, Cho, Hana, Kang, Jong-Sun
Natura: Artigo
Lingua:Inglês
Pubblicazione: National Academy of Sciences 2017
Soggetti:
PNAS Plus
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5338397/
https://ncbi.nlm.nih.gov/pubmed/28154134
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1615105114
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