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Cdon deficiency causes cardiac remodeling through hyperactivation of WNT/β-catenin signaling
On pathological stress, Wnt signaling is reactivated and induces genes associated with cardiac remodeling and fibrosis. We have previously shown that a cell surface receptor Cdon (cell-adhesion associated, oncogene regulated) suppresses Wnt signaling to promote neuronal differentiation however its r...
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| Veröffentlicht in: | Proc Natl Acad Sci U S A |
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| Hauptverfasser: | , , , , , , , , , , |
| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
National Academy of Sciences
2017
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5338397/ https://ncbi.nlm.nih.gov/pubmed/28154134 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1615105114 |
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