AXL-dependent infection of human fetal endothelial cells distinguishes Zika virus from other pathogenic flaviviruses

Although a causal relationship between Zika virus (ZIKV) and microcephaly has been established, it remains unclear why ZIKV, but not other pathogenic flaviviruses, causes congenital defects. Here we show that when viruses are produced in mammalian cells, ZIKV, but not the closely related dengue viru...

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Dettagli Bibliografici
Pubblicato in:Proc Natl Acad Sci U S A
Autori principali: Richard, Audrey Stéphanie, Shim, Byoung-Shik, Kwon, Young-Chan, Zhang, Rong, Otsuka, Yuka, Schmitt, Kimberly, Berri, Fatma, Diamond, Michael S., Choe, Hyeryun
Natura: Artigo
Lingua:Inglês
Pubblicazione: National Academy of Sciences 2017
Soggetti:
Biological Sciences
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5338370/
https://ncbi.nlm.nih.gov/pubmed/28167751
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1620558114
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