Zika Virus-Immune Plasmas from Symptomatic and Asymptomatic Individuals Enhance Zika Pathogenesis in Adult and Pregnant Mice

Preexisting immunity against dengue virus or West Nile virus was previously reported to mediate antibody-dependent enhancement (ADE) of Zika virus (ZIKV) infection in a mouse model. We show here that ZIKV-immune plasma samples from both symptomatic and asymptomatic individuals mediated ZIKV ADE of i...

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Detalhes bibliográficos
Publicado no:mBio
Main Authors: Shim, Byoung-Shik, Kwon, Young-Chan, Ricciardi, Michael J., Stone, Mars, Otsuka, Yuka, Berri, Fatma, Kwal, Jaclyn M., Magnani, Diogo M., Jackson, Cody B., Richard, Audrey S., Norris, Philip, Busch, Michael, Curry, Christine L., Farzan, Michael, Watkins, David, Choe, Hyeryun
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2019
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Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6606798/
https://ncbi.nlm.nih.gov/pubmed/31266863
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/mBio.00758-19
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