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AXL-dependent infection of human fetal endothelial cells distinguishes Zika virus from other pathogenic flaviviruses

Although a causal relationship between Zika virus (ZIKV) and microcephaly has been established, it remains unclear why ZIKV, but not other pathogenic flaviviruses, causes congenital defects. Here we show that when viruses are produced in mammalian cells, ZIKV, but not the closely related dengue viru...

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Bibliografske podrobnosti
izdano v:Proc Natl Acad Sci U S A
Main Authors: Richard, Audrey Stéphanie, Shim, Byoung-Shik, Kwon, Young-Chan, Zhang, Rong, Otsuka, Yuka, Schmitt, Kimberly, Berri, Fatma, Diamond, Michael S., Choe, Hyeryun
Format: Artigo
Jezik:Inglês
Izdano: National Academy of Sciences 2017
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC5338370/
https://ncbi.nlm.nih.gov/pubmed/28167751
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1620558114
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