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AXL-dependent infection of human fetal endothelial cells distinguishes Zika virus from other pathogenic flaviviruses

Although a causal relationship between Zika virus (ZIKV) and microcephaly has been established, it remains unclear why ZIKV, but not other pathogenic flaviviruses, causes congenital defects. Here we show that when viruses are produced in mammalian cells, ZIKV, but not the closely related dengue viru...

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Bibliografiske detaljer
Udgivet i:Proc Natl Acad Sci U S A
Main Authors: Richard, Audrey Stéphanie, Shim, Byoung-Shik, Kwon, Young-Chan, Zhang, Rong, Otsuka, Yuka, Schmitt, Kimberly, Berri, Fatma, Diamond, Michael S., Choe, Hyeryun
Format: Artigo
Sprog:Inglês
Udgivet: National Academy of Sciences 2017
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5338370/
https://ncbi.nlm.nih.gov/pubmed/28167751
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1620558114
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