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A temporal proteome dynamics study reveals the molecular basis of induced phenotypic resistance in Mycobacterium smegmatis at sub-lethal rifampicin concentrations

In the last 40 years only one new antitubercular drug has been approved, whilst resistance to current drugs, including rifampicin, is spreading. Here, we used the model organism Mycobacterium smegmatis to study mechanisms of phenotypic mycobacterial resistance, employing quantitative mass spectromet...

詳細記述

保存先:
書誌詳細
出版年:Sci Rep
主要な著者: Giddey, Alexander D., de Kock, Elise, Nakedi, Kehilwe C., Garnett, Shaun, Nel, Andrew J. M., Soares, Nelson C., Blackburn, Jonathan M.
フォーマット: Artigo
言語:Inglês
出版事項: Nature Publishing Group 2017
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC5338346/
https://ncbi.nlm.nih.gov/pubmed/28262820
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep43858
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