PRODUCTION OF A PRELIMINARY QUALITY CONTROL PIPELINE FOR SINGLE NUCLEI RNA-SEQ AND ITS APPLICATION IN THE ANALYSIS OF CELL TYPE DIVERSITY OF POST-MORTEM HUMAN BRAIN NEOCORTEX

Next generation sequencing of the RNA content of single cells or single nuclei (sc/nRNA-seq) has become a powerful approach to understand the cellular complexity and diversity of multicellular organisms and environmental ecosystems. However, the fact that the procedure begins with a relatively small...

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Detalhes bibliográficos
Publicado no:Pac Symp Biocomput
Principais autores: Aevermann, Brian, McCorrison, Jamison, Venepally, Pratap, Hodge, Rebecca, Bakken, Trygve, Miller, Jeremy, Novotny, Mark, Tran, Danny N., Diez-Fuertes, Francisco, Christiansen, Lena, Zhang, Fan, Steemers, Frank, Lasken, Roger S., Lein, Ed, Schork, Nicholas, Scheuermann, Richard H.
Formato: Artigo
Idioma:Inglês
Publicado em: 2016
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5338304/
https://ncbi.nlm.nih.gov/pubmed/27897007
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