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Cell type discovery using single-cell transcriptomics: implications for ontological representation

Cells are fundamental function units of multicellular organisms, with different cell types playing distinct physiological roles in the body. The recent advent of single-cell transcriptional profiling using RNA sequencing is producing ‘big data’, enabling the identification of novel human cell types...

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Detalhes bibliográficos
Publicado no:Hum Mol Genet
Main Authors: Aevermann, Brian D, Novotny, Mark, Bakken, Trygve, Miller, Jeremy A, Diehl, Alexander D, Osumi-Sutherland, David, Lasken, Roger S, Lein, Ed S, Scheuermann, Richard H
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5946857/
https://ncbi.nlm.nih.gov/pubmed/29590361
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/hmg/ddy100
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