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NeatFreq: reference-free data reduction and coverage normalization for De Novo sequence assembly

BACKGROUND: Deep shotgun sequencing on next generation sequencing (NGS) platforms has contributed significant amounts of data to enrich our understanding of genomes, transcriptomes, amplified single-cell genomes, and metagenomes. However, deep coverage variations in short-read data sets and high seq...

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Detalhes bibliográficos
Publicado no:BMC Bioinformatics
Main Authors: McCorrison, Jamison M, Venepally, Pratap, Singh, Indresh, Fouts, Derrick E, Lasken, Roger S, Methé, Barbara A
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4245761/
https://ncbi.nlm.nih.gov/pubmed/25407910
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12859-014-0357-3
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