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The interplay between effector binding and allostery in an engineered protein switch
The protein design rules for engineering allosteric regulation are not well understood. A fundamental understanding of the determinants of ligand binding in an allosteric context could facilitate the design and construction of versatile protein switches and biosensors. Here, we conducted extensive i...
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| Veröffentlicht in: | Protein Sci |
|---|---|
| Hauptverfasser: | , , |
| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
John Wiley and Sons Inc.
2016
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5338240/ https://ncbi.nlm.nih.gov/pubmed/27272021 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/pro.2962 |
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