Aspirin-induced chemoprevention and response kinetics are enhanced by PIK3CA mutations in colorectal cancer cells

This study was designed to determine how aspirin influences the growth kinetics and characteristics of cultured colorectal cancer (CRC) cells that harbor a variety of different mutational backgrounds, including PIK3CA and KRAS activating mutations and the presence or absence of microsatellite instab...

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Bibliografske podrobnosti
izdano v:Cancer Prev Res (Phila)
Main Authors: Zumwalt, Timothy J, Wodarz, Dominik, Komarova, Natalia L, Toden, Shusuke, Turner, Jacob, Cardenas, Jacob, Burn, John, Chan, Andrew T, Boland, C Richard, Goel, Ajay
Format: Artigo
Jezik:Inglês
Izdano: 2017
Teme:
Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC5337164/
https://ncbi.nlm.nih.gov/pubmed/28154202
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/1940-6207.CAPR-16-0175
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