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Aspirin-induced chemoprevention and response kinetics are enhanced by PIK3CA mutations in colorectal cancer cells

This study was designed to determine how aspirin influences the growth kinetics and characteristics of cultured colorectal cancer (CRC) cells that harbor a variety of different mutational backgrounds, including PIK3CA and KRAS activating mutations and the presence or absence of microsatellite instab...

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Detalles Bibliográficos
Publicado en:Cancer Prev Res (Phila)
Autores principales: Zumwalt, Timothy J, Wodarz, Dominik, Komarova, Natalia L, Toden, Shusuke, Turner, Jacob, Cardenas, Jacob, Burn, John, Chan, Andrew T, Boland, C Richard, Goel, Ajay
Formato: Artigo
Lenguaje:Inglês
Publicado: 2017
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC5337164/
https://ncbi.nlm.nih.gov/pubmed/28154202
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/1940-6207.CAPR-16-0175
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