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Methylation kinetics and CpG-island methylator phenotyope status in colorectal cancer cell lines
BACKGROUND: Hypermethylation of CpG islands is thought to contribute to carcinogenesis through the inactivation of tumor suppressor genes. Tumor cells with relatively high levels of CpG island methylation are considered CpG island methylator phenotypes (CIMP). The mechanisms that are responsible for...
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| Main Authors: | , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
BioMed Central
2013
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3691599/ https://ncbi.nlm.nih.gov/pubmed/23758948 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1745-6150-8-14 |
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