Stage-specific human induced pluripotent stem cells map the progression of myeloid transformation to transplantable leukemia

Myeloid malignancy is increasingly viewed as a disease spectrum, comprising hematopoietic disorders that extend across a phenotypic continuum ranging from clonal hematopoiesis to myelodysplastic syndrome (MDS) and acute myeloid leukemia (AML). In this study, we derived a collection of iPSC lines cap...

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Detalhes bibliográficos
Publicado no:Cell Stem Cell
Main Authors: Kotini, Andriana G, Chang, Chan-Jung, Chow, Arthur, Yuan, Han, Ho, Tzu-Chieh, Wang, Tiansu, Vora, Shailee, Solovyov, Alexander, Husser, Chrystel, Olszewska, Malgorzata, Teruya-Feldstein, Julie, Perumal, Deepak, Klimek, Virginia M, Spyridonidis, Alexandros, Rampal, Raajit K, Silverman, Lewis, Reddy, E Premkumar, Papaemmanuil, Elli, Parekh, Samir, Greenbaum, Benjamin D, Leslie, Christina S, Kharas, Michael G, Papapetrou, Eirini P
Formato: Artigo
Idioma:Inglês
Publicado em: 2017
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5337161/
https://ncbi.nlm.nih.gov/pubmed/28215825
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.stem.2017.01.009
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