Llwytho...

Engineering of targeted megabase-scale deletions in human induced pluripotent stem cells

Recurrent chromosomal deletions spanning several megabases are often found in hematological malignancies. The ability to engineer deletions in model systems to functionally study their effects on the phenotype would enable, first, determination of whether a given deletion is pathogenic or neutral an...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:Exp Hematol
Prif Awduron: Kotini, Andriana G., Papapetrou, Eirini P.
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: 2020
Pynciau:
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC7816568/
https://ncbi.nlm.nih.gov/pubmed/32544417
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.exphem.2020.06.001
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