Capsaicin Synergizes with Camptothecin to Induce Increased Apoptosis in Human Small Cell Lung Cancers via the Calpain Pathway

Small cell lung cancer (SCLC) is characterized by excellent initial response to chemotherapy and radiation therapy with a majority of the patients showing tumor shrinkage and even remission. However, the challenge with SCLC therapy is that patients inevitably relapse and subsequently do not respond...

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Pubblicato in:Biochem Pharmacol
Autori principali: Friedman, Jamie R., Perry, Haley E., Brown, Kathleen C., Gao, Yin, Lin, Ju, Stevenson, Cathyrn D., Hurley, John D., Nolan, Nicholas A., Akers, Austin T., Chen, Yi Charlie, Denning, Krista L., Brown, Linda G., Dasgupta, Piyali
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2017
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Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5336517/
https://ncbi.nlm.nih.gov/pubmed/28104436
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bcp.2017.01.004
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