Capsaicin Induces Apoptosis in Human Small Cell Lung Cancer via the TRPV6 Receptor and the Calpain Pathway

Capsaicin, the pungent ingredient of chili peppers, displays potent anti-neoplastic activity in a wide array of human cancer cells. The present manuscript examines the signaling pathways underlying the apoptotic activity of capsaicin in human small cell lung cancer (SCLC) in vitro and in vivo. Studi...

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Hoofdauteurs: Lau, Jamie K., Brown, Kathleen C., Dom, Aaron M., Witte, Theodore R., Thornhill, Brent A., Crabtree, Clayton M., Perry, Haley E., Brown, J. Michael, Ball, John G., Creel, Rebecca G., Damron, C. Luke, Rollyson, William D., Stevenson, Cathryn D., Hardman, W. Elaine, Valentovic, Monica A., Carpenter, A. Betts, Dasgupta, Piyali
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: 2014
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Article
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4072851/
https://ncbi.nlm.nih.gov/pubmed/24878626
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s10495-014-1007-y
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