Capsaicin Displays Anti-Proliferative Activity against Human Small Cell Lung Cancer in Cell Culture and Nude Mice Models via the E2F Pathway

BACKGROUND: Small cell lung cancer (SCLC) is characterized by rapid progression and low survival rates. Therefore, novel therapeutic agents are urgently needed for this disease. Capsaicin, the active ingredient of chilli peppers, displays anti-proliferative activity in prostate and epidermoid cancer...

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Main Authors: Brown, Kathleen C., Witte, Ted R., Hardman, W. Elaine, Luo, Haitao, Chen, Yi C., Carpenter, A. Betts, Lau, Jamie K., Dasgupta, Piyali
Format: Artigo
Sprog:Inglês
Udgivet: Public Library of Science 2010
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2857654/
https://ncbi.nlm.nih.gov/pubmed/20421925
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0010243
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