Polypyrimidine Tract-Binding Protein 1 promotes proliferation, migration and invasion in clear-cell renal cell carcinoma by regulating alternative splicing of PKM

Polypyrimidine Tract-Binding Protein 1 (PTBP1) is an essential RNA-binding protein that regulates diverse biological events through regulating alternative splice of mRNA. PTBP1 induces cancer-promoting splice variants and is related to tumorigenesis in several cancers. However, both the expression p...

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Bibliografiska uppgifter
I publikationen:Am J Cancer Res
Huvudupphovsmän: Jiang, Junyi, Chen, Xu, Liu, Hao, Shao, Jing, Xie, Ruihui, Gu, Peng, Duan, Chaohui
Materialtyp: Artigo
Språk:Inglês
Publicerad: e-Century Publishing Corporation 2017
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Original Article
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC5336499/
https://ncbi.nlm.nih.gov/pubmed/28337374
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