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Networks of Dynamic Allostery Regulate Enzyme Function

Many protein systems rely on coupled dynamic networks to allosterically regulate function. However, the broad conformational space sampled by non-coherently dynamic systems has precluded detailed analysis of their communication mechanisms. Here, we have developed a methodology that combines the high...

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Detalles Bibliográficos
Publicado en:Structure
Main Authors: Holliday, Michael Joseph, Camilloni, Carlo, Armstrong, Geoffrey Stuart, Vendruscolo, Michele, Eisenmesser, Elan Zohar
Formato: Artigo
Idioma:Inglês
Publicado: 2017
Assuntos:
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC5336394/
https://ncbi.nlm.nih.gov/pubmed/28089447
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.str.2016.12.003
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