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Modulating Enzyme Function via Dynamic Allostery within Biliverdin Reductase B

The biliverdin reductase B (BLVRB) class of enzymes catalyze the NADPH-dependent reduction of multiple flavin substrates and are emerging as critical players in cellular redox regulation. However, the role of dynamics and allostery have not been addressed, prompting studies here that have revealed a...

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Detalhes bibliográficos
Publicado no:Front Mol Biosci
Main Authors: Redzic, Jasmina S., Duff, Michael R., Blue, Ashley, Pitts, Todd M., Agarwal, Pratul, Eisenmesser, Elan Zohar
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2021
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC8173106/
https://ncbi.nlm.nih.gov/pubmed/34095235
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fmolb.2021.691208
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