miR-21-mediated Radioresistance Occurs via Promoting Repair of DNA Double Strand Breaks

miR-21, as an oncogene that overexpresses in most human tumors, is involved in radioresistance; however, the mechanism remains unclear. Here, we demonstrate that miR-21-mediated radioresistance occurs through promoting repair of DNA double strand breaks, which includes facilitating both non-homologo...

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Detalhes bibliográficos
Publicado no:J Biol Chem
Main Authors: Hu, Baocheng, Wang, Xiang, Hu, Shuofeng, Ying, Xiaomin, Wang, Ping, Zhang, Xiangming, Wang, Jian, Wang, Hongyan, Wang, Ya
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2017
Assuntos:
Cell Biology
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5336183/
https://ncbi.nlm.nih.gov/pubmed/28096467
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M116.772392
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