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MicroRNA-processing Enzymes Are Essential for Survival and Function of Mature Retinal Pigmented Epithelial Cells in Mice

Age-related macular degeneration (AMD) is a major cause of irreversible vision loss. The neovascular or “wet” form of AMD can be treated to varying degrees with anti-angiogenic drugs, but geographic atrophy (GA) is an advanced stage of the more prevalent “dry” form of AMD for which there is no effec...

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Detalhes bibliográficos
Publicado no:J Biol Chem
Main Authors: Sundermeier, Thomas R., Sakami, Sanae, Sahu, Bhubanananda, Howell, Scott J., Gao, Songqi, Dong, Zhiqian, Golczak, Marcin, Maeda, Akiko, Palczewski, Krzysztof
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5336169/
https://ncbi.nlm.nih.gov/pubmed/28104803
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M116.770024
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