The Activating C-type Lectin-like Receptor NKp65 Signals through a Hemi-immunoreceptor Tyrosine-based Activation Motif (hemITAM) and Spleen Tyrosine Kinase (Syk)

NKp65 is an activating human C-type lectin-like receptor (CTLR) triggering cellular cytotoxicity and cytokine secretion upon high-affinity interaction with the cognate CTLR keratinocyte-associated C-type lectin (KACL) selectively expressed by human keratinocytes. Previously, we demonstrated that NKp...

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Detalhes bibliográficos
Publicado no:J Biol Chem
Main Authors: Bauer, Björn, Wotapek, Tanja, Zöller, Tobias, Rutkowski, Emilia, Steinle, Alexander
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2017
Assuntos:
Immunology
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5336157/
https://ncbi.nlm.nih.gov/pubmed/28082678
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M116.759977
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