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Limitations and challenges of genetic barcode quantification

Genetic barcodes are increasingly used to track individual cells and to quantitatively assess their clonal contributions over time. Although barcode quantification relies entirely on counting sequencing reads, detailed studies about the method’s accuracy are still limited. We report on a systematic...

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Detalles Bibliográficos
Publicado en:Sci Rep
Main Authors: Thielecke, Lars, Aranyossy, Tim, Dahl, Andreas, Tiwari, Rajiv, Roeder, Ingo, Geiger, Hartmut, Fehse, Boris, Glauche, Ingmar, Cornils, Kerstin
Formato: Artigo
Idioma:Inglês
Publicado: Nature Publishing Group 2017
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC5335698/
https://ncbi.nlm.nih.gov/pubmed/28256524
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep43249
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