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Stem Cell Proliferation and Quiescence—Two Sides of the Same Coin

The kinetics of label uptake and dilution in dividing stem cells, e.g., using Bromodeoxyuridine (BrdU) as a labeling substance, are a common way to assess the cellular turnover of all hematopoietic stem cells (HSCs) in vivo. The assumption that HSCs form a homogeneous population of cells which regul...

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Detalhes bibliográficos
Main Authors: Glauche, Ingmar, Moore, Kateri, Thielecke, Lars, Horn, Katrin, Loeffler, Markus, Roeder, Ingo
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2704962/
https://ncbi.nlm.nih.gov/pubmed/19629161
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pcbi.1000447
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