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An inflammatory gene signature distinguishes neurofibroma Schwann cells and macrophages from cells in the normal peripheral nervous system

Neurofibromas are benign peripheral nerve tumors driven by NF1 loss in Schwann cells (SCs). Macrophages are abundant in neurofibromas, and macrophage targeted interventions may have therapeutic potential in these tumors. We generated gene expression data from fluorescence-activated cell sorted (FACS...

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Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:Sci Rep
Prif Awduron: Choi, Kwangmin, Komurov, Kakajan, Fletcher, Jonathan S., Jousma, Edwin, Cancelas, Jose A., Wu, Jianqiang, Ratner, Nancy
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: Nature Publishing Group 2017
Pynciau:
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC5335359/
https://ncbi.nlm.nih.gov/pubmed/28256556
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep43315
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