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Neurofibroma-associated macrophages play roles in tumor growth and response to pharmacological inhibition

Neurofibromatosis type 1 (NF1) is a common genetic disease that predisposes 30–50 % of affected individuals to develop plexiform neurofibromas. We found that macrophage infiltration of both mouse and human neurofibromas correlates with disease progression. Macrophages accounted for almost half of ne...

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Detalhes bibliográficos
Main Authors: Prada, Carlos E., Jousma, Edwin, Rizvi, Tilat A., Wu, Jianqiang, Dunn, R. Scott, Mayes, Debra A., Cancelas, Jose A., Dombi, Eva, Kim, Mi-Ok, West, Brian L., Bollag, Gideon, Ratner, Nancy
Formato: Artigo
Idioma:Inglês
Publicado em: 2012
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3547628/
https://ncbi.nlm.nih.gov/pubmed/23099891
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00401-012-1056-7
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