Neurofibroma-associated macrophages play roles in tumor growth and response to pharmacological inhibition

Neurofibromatosis type 1 (NF1) is a common genetic disease that predisposes 30–50 % of affected individuals to develop plexiform neurofibromas. We found that macrophage infiltration of both mouse and human neurofibromas correlates with disease progression. Macrophages accounted for almost half of ne...

Full description

Saved in:
Bibliographic Details
Main Authors: Prada, Carlos E., Jousma, Edwin, Rizvi, Tilat A., Wu, Jianqiang, Dunn, R. Scott, Mayes, Debra A., Cancelas, Jose A., Dombi, Eva, Kim, Mi-Ok, West, Brian L., Bollag, Gideon, Ratner, Nancy
Format: Artigo
Language:Inglês
Published: 2012
Subjects:
Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3547628/
https://ncbi.nlm.nih.gov/pubmed/23099891
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00401-012-1056-7
Tags: Add Tag
No Tags, Be the first to tag this record!

Similar Items