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RNA polymerase III initiation on coligo DNA templates containing loops of variable sequence, size and nucleotide chemistry

Circularized oligonucleotides, or coligos, were previously found to serve as RNA polymerase III (Pol III) templates in vitro and in human tissue culture cells. Here we randomized the 12-nucleotide larger loop (L-loop) of a well characterized coligo and found unexpectedly that in vitro transcription...

Täydet tiedot

Tallennettuna:
Bibliografiset tiedot
Julkaisussa:Gene
Päätekijät: Patel, Joy, Lama, Lodoe, Hoffmann, Niklas A., Cobo, Jose, Müller, Christoph W., Ryan, Kevin
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: 2016
Aiheet:
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC5334452/
https://ncbi.nlm.nih.gov/pubmed/27593562
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.gene.2016.09.001
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