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Significance of Polymorphism and Expression of miR-146a and NFkB1 Genetic Variants in Patients with Rheumatoid Arthritis

MicroRNA-146a (miR-146a) has been shown to play an important role in the regulation of inflammatory innate immune responses, and found to be differentially expressed in rheumatoid arthritis (RA). Through NF-κB pathway, this molecule is able to stimulate the release of pro-inflammatory cytokines such...

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Publicado en:Arch Immunol Ther Exp (Warsz)
Autores principales: Bogunia-Kubik, Katarzyna, Wysoczańska, Barbara, Piątek, Dagmara, Iwaszko, Milena, Ciechomska, Marzena, Świerkot, Jerzy
Formato: Artigo
Lenguaje:Inglês
Publicado: Springer International Publishing 2017
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC5334424/
https://ncbi.nlm.nih.gov/pubmed/28083614
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00005-016-0443-5
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