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Influence of NKG2D Genetic Variants on Response to Anti-TNF Agents in Patients with Rheumatoid Arthritis

A natural killer group 2 member D (NKG2D) acts as a powerful activating and co-stimulatory receptor on immune effector cells including NK and T cells. Disruptions within the NKG2D signalling pathway may trigger an exacerbated immune response and promote autoimmune reactions. The objective of the stu...

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Bibliographic Details
Published in:Genes (Basel)
Main Authors: Iwaszko, Milena, Świerkot, Jerzy, Kolossa, Katarzyna, Jeka, Sławomir, Wiland, Piotr, Bogunia-Kubik, Katarzyna
Format: Artigo
Language:Inglês
Published: MDPI 2018
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC5852560/
https://ncbi.nlm.nih.gov/pubmed/29370129
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/genes9020064
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