Relationship Between Interleukin-6 −174G/C Genetic Variant and Efficacy of Methotrexate Treatment in Psoriatic Arthritis Patients

INTRODUCTION: The purpose of the study was to investigate whether single-nucleotide polymorphisms (SNPs) IL-6 −174 G/C and IL-6R Asp358Ala are associated with susceptibility to psoriatic arthritis (PsA) or affect response to treatment with methotrexate (MTX). PATIENTS AND METHODS: Seventy-four patie...

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Detalhes bibliográficos
Publicado no:Pharmgenomics Pers Med
Main Authors: Sokolik, Renata, Iwaszko, Milena, Świerkot, Jerzy, Wysoczańska, Barbara, Korman, Lucyna, Wiland, Piotr, Bogunia-Kubik, Katarzyna
Formato: Artigo
Idioma:Inglês
Publicado em: Dove 2021
Assuntos:
Original Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7850562/
https://ncbi.nlm.nih.gov/pubmed/33536774
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2147/PGPM.S264555
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