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The volume-regulated anion channel (LRRC8) in nodose neurons is sensitive to acidic pH

The leucine rich repeat containing protein 8A (LRRC8A), or SWELL1, is an essential component of the volume-regulated anion channel (VRAC) that is activated by cell swelling and ionic strength. We report here for the first time to our knowledge its expression in a primary cell culture of nodose gangl...

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Detalhes bibliográficos
Publicado no:JCI Insight
Main Authors: Wang, Runping, Lu, Yongjun, Gunasekar, Susheel, Zhang, Yanhui, Benson, Christopher J., Chapleau, Mark W., Sah, Rajan, Abboud, François M.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Clinical Investigation 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5333957/
https://ncbi.nlm.nih.gov/pubmed/28289711
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/jci.insight.90632
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