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Th17 cells are refractory to senescence and retain robust antitumor activity after long-term ex vivo expansion
Adoptive immunotherapy for solid tumors relies on infusing large numbers of T cells to mediate successful antitumor responses in patients. While long-term rapid-expansion protocols (REPs) produce sufficient numbers of CD8(+) T cells for treatment, they also cause decline in the cell’s therapeutic fi...
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| Опубликовано в: : | JCI Insight |
|---|---|
| Главные авторы: | , , , , , , , , |
| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
American Society for Clinical Investigation
2017
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| Предметы: | |
| Online-ссылка: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5333954/ https://ncbi.nlm.nih.gov/pubmed/28289713 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/jci.insight.90772 |
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