Cargando...
Scalable Design of Paired CRISPR Guide RNAs for Genomic Deletion
CRISPR-Cas9 technology can be used to engineer precise genomic deletions with pairs of single guide RNAs (sgRNAs). This approach has been widely adopted for diverse applications, from disease modelling of individual loci, to parallelized loss-of-function screens of thousands of regulatory elements....
Gardado en:
| Publicado en: | PLoS Comput Biol |
|---|---|
| Main Authors: | , , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
Public Library of Science
2017
|
| Assuntos: | |
| Acceso en liña: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5333799/ https://ncbi.nlm.nih.gov/pubmed/28253259 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pcbi.1005341 |
| Tags: |
Engadir etiqueta
Sen Etiquetas, Sexa o primeiro en etiquetar este rexistro!
|