Upregulation of the endothelin A (ET(A)) receptor and its association with neurodegeneration in a rodent model of glaucoma

BACKGROUND: Primary open angle glaucoma is a heterogeneous group of optic neuropathies that results in optic nerve degeneration and a loss of retinal ganglion cells (RGCs) ultimately causing blindness if allowed to progress. Elevation of intraocular pressure (IOP) is the most attributable risk facto...

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Veröffentlicht in:BMC Neurosci
Hauptverfasser: McGrady, Nolan R., Minton, Alena Z., Stankowska, Dorota L., He, Shaoqing, Jefferies, Hayden B., Krishnamoorthy, Raghu R.
Format: Artigo
Sprache:Inglês
Veröffentlicht: BioMed Central 2017
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Research Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5333388/
https://ncbi.nlm.nih.gov/pubmed/28249604
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12868-017-0346-3
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