Agglutination by anti-capsular polysaccharide antibody is associated with protection against experimental human pneumococcal carriage

The ability of pneumococcal conjugate vaccine (PCV) to decrease transmission by blocking the acquisition of colonization has been attributed to herd immunity. We describe the role of mucosal IgG to capsular polysaccharide (CPS) in mediating protection from carriage, translating our findings from a m...

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Publicado en:Mucosal Immunol
Autores principales: Mitsi, E, Roche, AM, Reiné, J, Zangari, T, Owugha, JT, Pennington, SH, Gritzfeld, JF, Wright, AD, Collins, AM, van Selm, S, de Jonge, MI, Gordon, SB, Weiser, JN, Ferreira, DM
Formato: Artigo
Lenguaje:Inglês
Publicado: 2016
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Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC5332540/
https://ncbi.nlm.nih.gov/pubmed/27579859
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/mi.2016.71
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