Agglutination by anti-capsular polysaccharide antibody is associated with protection against experimental human pneumococcal carriage

The ability of pneumococcal conjugate vaccine (PCV) to decrease transmission by blocking the acquisition of colonization has been attributed to herd immunity. We describe the role of mucosal IgG to capsular polysaccharide (CPS) in mediating protection from carriage, translating our findings from a m...

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Detalhes bibliográficos
Publicado no:Mucosal Immunol
Main Authors: Mitsi, E, Roche, AM, Reiné, J, Zangari, T, Owugha, JT, Pennington, SH, Gritzfeld, JF, Wright, AD, Collins, AM, van Selm, S, de Jonge, MI, Gordon, SB, Weiser, JN, Ferreira, DM
Formato: Artigo
Idioma:Inglês
Publicado em: 2016
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5332540/
https://ncbi.nlm.nih.gov/pubmed/27579859
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/mi.2016.71
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