Agglutination by anti-capsular polysaccharide antibody is associated with protection against experimental human pneumococcal carriage

The ability of pneumococcal conjugate vaccine (PCV) to decrease transmission by blocking the acquisition of colonization has been attributed to herd immunity. We describe the role of mucosal IgG to capsular polysaccharide (CPS) in mediating protection from carriage, translating our findings from a m...

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Bibliografische gegevens
Gepubliceerd in:Mucosal Immunol
Hoofdauteurs: Mitsi, E, Roche, AM, Reiné, J, Zangari, T, Owugha, JT, Pennington, SH, Gritzfeld, JF, Wright, AD, Collins, AM, van Selm, S, de Jonge, MI, Gordon, SB, Weiser, JN, Ferreira, DM
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: 2016
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Article
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5332540/
https://ncbi.nlm.nih.gov/pubmed/27579859
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/mi.2016.71
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