Importance of Salmonella Typhi-Responsive CD8+ T Cell Immunity in a Human Typhoid Fever Challenge Model

Typhoid fever, caused by the human-restricted organism Salmonella enterica serovar Typhi (S. Typhi), constitutes a major global health problem. The development of improved attenuated vaccines is pressing, but delayed by the lack of appropriate preclinical models. Herein, we report that high levels o...

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Detalles Bibliográficos
Publicado en:Front Immunol
Main Authors: Fresnay, Stephanie, McArthur, Monica A., Magder, Laurence S., Darton, Thomas C., Jones, Claire, Waddington, Claire S., Blohmke, Christoph J., Angus, Brian, Levine, Myron M., Pollard, Andrew J., Sztein, Marcelo B.
Formato: Artigo
Idioma:Inglês
Publicado: Frontiers Media S.A. 2017
Assuntos:
Immunology
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC5332428/
https://ncbi.nlm.nih.gov/pubmed/28303138
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fimmu.2017.00208
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