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SUN2 Silencing Impairs CD4 T Cell Proliferation and Alters Sensitivity to HIV-1 Infection Independently of Cyclophilin A

Linker of nucleoskeleton and cytoskeleton (LINC) complexes connect the nucleus to the cytoskeleton in eukaryotic cells. We previously reported that the overexpression of SUN2, an inner nuclear membrane protein and LINC complex component, inhibits HIV infection between the steps of reverse transcript...

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Bibliographic Details
Published in:J Virol
Main Authors: Donahue, Daniel A., Porrot, Françoise, Couespel, Norbert, Schwartz, Olivier
Format: Artigo
Language:Inglês
Published: American Society for Microbiology 2017
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC5331816/
https://ncbi.nlm.nih.gov/pubmed/28077629
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.02303-16
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