MAVS Is Essential for Primary CD4(+) T Cell Immunity but Not for Recall T Cell Responses following an Attenuated West Nile Virus Infection

The use of pathogen recognition receptor (PRR) agonists and the molecular mechanisms involved have been the major focus of research in individual vaccine development. West Nile virus (WNV) nonstructural (NS) 4B-P38G mutant has several features for an ideal vaccine candidate, including significantly...

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Bibliographische Detailangaben
Veröffentlicht in:J Virol
Hauptverfasser: Luo, Huanle, Winkelmann, Evandro, Xie, Guorui, Fang, Rong, Peng, Bi-Hung, Li, Li, Lazear, Helen M., Paessler, Slobodan, Diamond, Michael S., Gale, Michael, Barrett, Alan D., Wang, Tian
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society for Microbiology 2017
Schlagworte:
Pathogenesis and Immunity
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5331791/
https://ncbi.nlm.nih.gov/pubmed/28077630
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.02097-16
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