MAVS Is Essential for Primary CD4(+) T Cell Immunity but Not for Recall T Cell Responses following an Attenuated West Nile Virus Infection

The use of pathogen recognition receptor (PRR) agonists and the molecular mechanisms involved have been the major focus of research in individual vaccine development. West Nile virus (WNV) nonstructural (NS) 4B-P38G mutant has several features for an ideal vaccine candidate, including significantly...

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Detalhes bibliográficos
Publicado no:J Virol
Main Authors: Luo, Huanle, Winkelmann, Evandro, Xie, Guorui, Fang, Rong, Peng, Bi-Hung, Li, Li, Lazear, Helen M., Paessler, Slobodan, Diamond, Michael S., Gale, Michael, Barrett, Alan D., Wang, Tian
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2017
Assuntos:
Pathogenesis and Immunity
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5331791/
https://ncbi.nlm.nih.gov/pubmed/28077630
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.02097-16
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