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Continuous N-alkylation reactions of amino alcohols using γ-Al(2)O(3) and supercritical CO(2): unexpected formation of cyclic ureas and urethanes by reaction with CO(2)

The use of γ-Al(2)O(3) as a heterogeneous catalyst in scCO(2) has been successfully applied to the amination of alcohols for the synthesis of N-alkylated heterocycles. The optimal reaction conditions (temperature and substrate flow rate) were determined using an automated self-optimising reactor, re...

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Detaylı Bibliyografya
Yayımlandı:Beilstein J Org Chem
Asıl Yazarlar: Streng, Emilia S, Lee, Darren S, George, Michael W, Poliakoff, Martyn
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: Beilstein-Institut 2017
Konular:
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC5331277/
https://ncbi.nlm.nih.gov/pubmed/28326142
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3762/bjoc.13.36
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