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A CMC1‐knockout reveals translation‐independent control of human mitochondrial complex IV biogenesis
Defects in mitochondrial respiratory chain complex IV (CIV) frequently cause encephalocardiomyopathies. Human CIV assembly involves 14 subunits of dual genetic origin and multiple nucleus‐encoded ancillary factors. Biogenesis of the mitochondrion‐encoded copper/heme‐containing COX1 subunit initiates...
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| Gepubliceerd in: | EMBO Rep |
|---|---|
| Hoofdauteurs: | , |
| Formaat: | Artigo |
| Taal: | Inglês |
| Gepubliceerd in: |
John Wiley and Sons Inc.
2017
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| Onderwerpen: | |
| Online toegang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5331208/ https://ncbi.nlm.nih.gov/pubmed/28082314 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.15252/embr.201643103 |
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