Role of Twin Cys-Xaa(9)-Cys Motif Cysteines in Mitochondrial Import of the Cytochrome c Oxidase Biogenesis Factor Cmc1

The Mia40 import pathway facilitates the import and oxidative folding of cysteine-rich protein substrates into the mitochondrial intermembrane space. Here we describe the in vitro and in organello oxidative folding of Cmc1, a twin CX(9)C-containing substrate, which contains an unpaired cysteine. In...

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Main Authors: Bourens, Myriam, Dabir, Deepa V., Tienson, Heather L., Sorokina, Irina, Koehler, Carla M., Barrientos, Antoni
Formato: Artigo
Idioma:Inglês
Publicado: American Society for Biochemistry and Molecular Biology 2012
Assuntos:
Membrane Biology
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC3438957/
https://ncbi.nlm.nih.gov/pubmed/22767599
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M112.383562
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