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A CMC1‐knockout reveals translation‐independent control of human mitochondrial complex IV biogenesis

Defects in mitochondrial respiratory chain complex IV (CIV) frequently cause encephalocardiomyopathies. Human CIV assembly involves 14 subunits of dual genetic origin and multiple nucleus‐encoded ancillary factors. Biogenesis of the mitochondrion‐encoded copper/heme‐containing COX1 subunit initiates...

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Detalles Bibliográficos
Publicado en:EMBO Rep
Main Authors: Bourens, Myriam, Barrientos, Antoni
Formato: Artigo
Idioma:Inglês
Publicado: John Wiley and Sons Inc. 2017
Assuntos:
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC5331208/
https://ncbi.nlm.nih.gov/pubmed/28082314
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.15252/embr.201643103
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