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A CMC1‐knockout reveals translation‐independent control of human mitochondrial complex IV biogenesis

Defects in mitochondrial respiratory chain complex IV (CIV) frequently cause encephalocardiomyopathies. Human CIV assembly involves 14 subunits of dual genetic origin and multiple nucleus‐encoded ancillary factors. Biogenesis of the mitochondrion‐encoded copper/heme‐containing COX1 subunit initiates...

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Publicado en:EMBO Rep
Autores principales: Bourens, Myriam, Barrientos, Antoni
Formato: Artigo
Lenguaje:Inglês
Publicado: John Wiley and Sons Inc. 2017
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC5331208/
https://ncbi.nlm.nih.gov/pubmed/28082314
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.15252/embr.201643103
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