Immunostimulated Arginase II Expression in Intestinal Epithelial Cells Reduces Nitric Oxide Production and Apoptosis

Increased production of nitric oxide (NO) and subsequent local cytotoxicity to mucosal epithelial cells has been proposed as a putative mechanism involved in the development of necrotizing enterocolitis (NEC). Intestinal epithelial cells (IECs) metabolize L-arginine to either nitric oxide (NO) by NO...

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Detalhes bibliográficos
Publicado no:Front Cell Dev Biol
Main Authors: Talavera, Maria M., Nuthakki, Sushma, Cui, Hongmei, Jin, Yi, Liu, Yusen, Nelin, Leif D.
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2017
Assuntos:
Cell and Developmental Biology
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5331049/
https://ncbi.nlm.nih.gov/pubmed/28299311
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fcell.2017.00015
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